Neutrino Constraints on Inelastic Dark Matter after CDMS II

We discuss the neutrino constraints from solar and terrestrial dark matter (DM) annihilations in the inelastic dark matter (iDM) scenario after the recent CDMS II results. To reconcile the DAMA/LIBRA data with constraints from all other direct experiments, the iDM needs to be light ($m_\chi < 100$ GeV) and have a large DM-nucleon cross section ($\sigma_n \sim$ 10$^{-4}$ pb in the spin-independent (SI) scattering and $\sigma_n \sim$ 10 pb in the spin-dependent (SD) scattering). The dominant contribution to the iDM capture in the Sun is from scattering off Fe/Al in the SI/SD case. Current bounds from Super-Kamiokande exclude the hard DM annihilation channels, such as $W^+W^-$, $ZZ$, $t\bar{t}$ and $\tau^+ \tau^-$. For soft channels such as $b\bar{b}$ and $c \bar{c}$, the limits are loose, but could be tested or further constrained by future IceCube plus DeepCore. For neutrino constraints from the DM annihilation in the Earth, due to the weaker gravitational effect of the Earth and inelastic capture condition, the constraint exists only for small mass splitting $\delta <$ 40 keV and $m_\chi \sim (10, 50)$ GeV even in the $\tau^+ \tau^-$ channel.Comment: 11 pages, 8 figure

Design and Performance of the XENON10 Dark Matter Experiment

XENON10 is the first two-phase xenon time projection chamber (TPC) developed within the XENON dark matter search program. The TPC, with an active liquid xenon (LXe) mass of about 14 kg, was installed at the Gran Sasso underground laboratory (LNGS) in Italy, and operated for more than one year, with excellent stability and performance. Results from a dark matter search with XENON10 have been published elsewhere. In this paper, we summarize the design and performance of the detector and its subsystems, based on calibration data using sources of gamma-rays and neutrons as well as background and Monte Carlo simulations data. The results on the detector's energy threshold, energy and position resolution, and overall efficiency show a performance that exceeds design specifications, in view of the very low energy threshold achieved (<10 keVr) and the excellent energy resolution achieved by combining the ionization and scintillation signals, detected simultaneously

Discrete dark matter

We propose a new motivation for the stability of dark matter (DM). We suggest that the same non-abelian discrete flavor symmetry which accounts for the observed pattern of neutrino oscillations, spontaneously breaks to a Z2 subgroup which renders DM stable. The simplest scheme leads to a scalar doublet DM potentially detectable in nuclear recoil experiments, inverse neutrino mass hierarchy, hence a neutrinoless double beta decay rate accessible to upcoming searches, while reactor angle equal to zero gives no CP violation in neutrino oscillations.Comment: minor changes to match version accepted in PRD, one reference adde

Analysis of the XENON100 Dark Matter Search Data

The XENON100 experiment, situated in the Laboratori Nazionali del Gran Sasso, aims at the direct detection of dark matter in the form of weakly interacting massive particles (WIMPs), based on their interactions with xenon nuclei in an ultra low background dual-phase time projection chamber. This paper describes the general methods developed for the analysis of the XENON100 data. These methods have been used in the 100.9 and 224.6 live days science runs from which results on spin-independent elastic, spin-dependent elastic and inelastic WIMP-nucleon cross-sections have already been reported.Comment: 18 pages, 17 figures, information for the 224.6 live days run include

The MEGA Advanced Compton Telescope Project

The goal of the Medium Energy Gamma-ray Astronomy (MEGA) telescope is to improve sensitivity at medium gamma-ray energies (0.4-50 MeV) by at least an order of magnitude over that of COMPTEL. This will be achieved with a new compact design that allows for a very wide field of view, permitting a sensitive all-sky survey and the monitoring of transient and variable sources. The key science objectives for MEGA include the investigation of cosmic high-energy particle accelerators, studies of nucleosynthesis sites using gamma-ray lines, and determination of the large-scale structure of galactic and cosmic diffuse background emission. MEGA records and images gamma-ray events by completely tracking both Compton and pair creation interactions in a tracker of double-sided silicon strip detectors and a calorimeter of CsI crystals able to resolve in three dimensions. We present initial laboratory calibration results from a small prototype MEGA telescope.Comment: 7 pages LaTeX, 5 figures, to appear in New Astronomy Reviews (Proceedings of the Ringberg Workshop "Astronomy with Radioactivities III"

Sterile neutrino dark matter, CDMS-II and a light Higgs boson

We add a singlet right handed neutrino plus a charged and a neutral singlet scalars to the standard model. This extension includes a discrete symmetry such that we obtain a heavy sterile neutrino which couples only to the electron and the new scalars. In this sense the singlet neutrino does not mix with ordinary ones and thus has no effect on Big Bang Nucleosynthesis. However, such sterile neutrino can be in equilibrium with electroweak particles in the early Universe due to its couplings to electrons and also because the Higgs boson mixes with the singlet scalars. We obtain that the sterile neutrino constitutes a dark matter candidate and analyze its direct detection in the light of current experiments. Our results show that if such a sterile neutrino is realized in nature, and CDMS-II experiment confirms its positive signal, dark matter demands a rather light Higgs boson with new Physics at some 500 GeV scale.Comment: 16 pages, 13 figures, uses axodraw.st

Holographic Superconductors in a Cohesive Phase

We consider a four-dimensional N=2 gauged supergravity coupled to matter fields. The model is obtained by a U(1) gauging of a charged hypermultiplet and therefore it is suitable for the study of holographic superconductivity. The potential has a topologically flat direction and the parameter running on this "moduli space" labels the new superconducting black holes. Zero temperature solutions are constructed and the phase diagram of the theory is studied. The model has rich dynamics. The retrograde condensate is just a special case in the new class of black holes. The calculation of the entanglement entropy makes manifest the properties of a generic solution and the superconductor at zero temperature is in a confined cohesive phase. The parameter running on the topologically flat direction is a marginal coupling in the dual field theory. We prove this statement by considering the way double trace deformations are treated in the AdS/CFT correspondence. Finally, we comment on a possible connection, in the context of gauge/gravity dualities, between the geometry of the scalar manifold in N=2 supergravity models and the space of marginal deformations of the dual field theory.Comment: 32 pages, 11 figures. Introduction rewritten and clarified, comments and details on section 4 added, acknowledgements rectified. To appear in JHE

Quantum Gravity from Conformal Field Theory

We bootstrap loop corrections to AdS5 supergravity amplitudes by enforcing the consistency of the known classical results with the operator product expansion of NN = 4 super Yang-Mills theory. In particular this yields much new information on the spectrum of double-trace operators which can then be used, in combination with superconformal symmetry and crossing symmetry, to obtain a prediction for the one-loop amplitude for four graviton multiplets in AdS. This in turn yields further new results on subleading O(1/N 4) corrections to certain double-trace anomalous dimensions

A chemical mutagenesis approach to insert post-translational modifications in aggregation-prone proteins

Neurodegenerative diseases are a class of disorders linked to the formation in the nervous system of fibrillar protein aggregates called amyloids. This aggregation process is affected by a variety of post-translational modifications, whose specific mechanisms are not fully understood yet. Emerging chemical mutagenesis technology is currently striving to address the challenge of introducing protein post-translational modifications, while maintaining the stability and solubility of the proteins during the modification reaction. Several amyloidogenic proteins are highly aggregation-prone, and current modification procedures can lead to unexpected precipitation of these proteins, affecting their yield and downstream characterization. Here, we present a method for maintaining amyloidogenic protein solubility during chemical mutagenesis. As proof-of-principle, we applied our method to mimic the phosphorylation of serine-26 and the acetylation of lysine-28 of the 40-residue long variant of amyloid-β peptide, whose aggregation is linked to Alzheimer’s disease

p-wave Holographic Superconductors and five-dimensional gauged Supergravity

We explore five-dimensional ${\cal N}=4$ $SU(2)\times U(1)$ and ${\cal N}=8$ SO(6) gauged supergravities as frameworks for condensed matter applications. These theories contain charged (dilatonic) black holes and 2-forms which have non-trivial quantum numbers with respect to U(1) subgroups of SO(6). A question of interest is whether they also contain black holes with two-form hair with the required asymptotic to give rise to holographic superconductivity. We first consider the ${\cal N}=4$ case, which contains a complex two-form potential $A_{\mu\nu}$ which has U(1) charge $\pm 1$. We find that a slight generalization, where the two-form potential has an arbitrary charge $q$, leads to a five-dimensional model that exhibits second-order superconducting transitions of p-wave type where the role of order parameter is played by $A_{\mu\nu}$, provided $q \gtrsim 5.6$. We identify the operator that condenses in the dual CFT, which is closely related to ${\cal N}=4$ Super Yang-Mills theory with chemical potentials. Similar phase transitions between R-charged black holes and black holes with 2-form hair are found in a generalized version of the ${\cal N}=8$ gauged supergravity Lagrangian where the two-forms have charge $q\gtrsim 1.8$.Comment: 35 pages, 14 figure